Tetramethylrhodamin (TAMRA) is a dye that can be used as a 3’-terminal (or internal) quencher for TaqMan® or Molecular Beacon probes with shorter-waved reporter dyes (FAM, TET, JOE, HEX, YAK, Cy3, VIC).

Currently dark quenchers are preferentially used for TaqMan® probes, since they are not fluorescent and therefore especially qualified not to generate interferences in multiplex applications.

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